Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0327056
PubChem CID
Molecular Formula
C16H19N5O
Molecular Weight
297.362 g/mol
Synonyms/Alias
[CHEMBL4474970; BDBM50532036]
InChI Key
DLKZJBMUUOOTSV-UHFFFAOYSA-N
InChI
InChI=1S/C16H19N5O/c22-15(17-14-9-11-6-7-13(14)8-11)10-21-19-16(18-20-21)12-4-2-1-3-5-12/h1-5,11,13-...
IUPAC Name
N-(2-bicyclo[2.2.1]heptanyl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS Number
5173-98-8

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

22 25 0 0 0 0 0 0 0 0999 V2000
-6.9923 -1.1830 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-5.6530 -1.8584 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.5967 -0...

Experimental Data

Activity Data

Target Ion Channel
ATP sensitive inward rectifier potassium channel 1
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 340 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
22
Rotatable Bonds
4
logP
1.6449
Complexity
80.6317
TPSA (Ų)
72.7
H-Bond Donors
1
H-Bond Acceptors
5
Ring Count
4
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